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. The composition of claim 1, wherein the first neurogenic agent is atorvastatin (CAS RN 134523-00-5), cerivastatin (CAS RN 145599-86-6), crilvastatin (CAS RN 120551-59-9), fluvastatin (CAS RN 93957-54-1), fluvastatin sodium (CAS RN 93957- 55-2), simvastatin (CAS RN 79902-63-9), lovastatin (CAS RN 75330-75-5), pravastatin (CAS RN 81093-37-0), pravastatin sodium (CAS RN 81131-70-6), rosuvastatin (CAS RN 287714-41-4), or simvastatin (CAS RN 79902-63-9); and. Advantageously, monoamine releasers provide a method for increasing levels of one or more monoamines within the synaptic cleft or other extracellular region independently of the activity of the presynaptic neuron. Phosphodiesterase (PDE) Agents [0232] In certain embodiments, one or more phosphodiesterase (PDE) antagonist agents are useful in combination with a first neurogenic agent of the present invention, ligandrol lgd-4033 before and after
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